China’s pursuit of sustainable and healthy economic growth requires the promotion of high-quality development. While many scholars have studied high-quality development, few have examined the coupling and coordination among its internal systems. The study aims to analyze the influencing factors of high-quality coordinated development, identify problem areas based on the five development statuses, and provide practical recommendations for optimizing the spatial layout of high-quality development in these areas. By applying a coupling coordination model and a geographically weighted regression model, the comprehensive level of high-quality coordinated development in the eastern coastal areas was evaluated. The results revealed that the majority of the eastern coastal region exhibited weak coordination and significant spatial differences in their comprehensive level. The problem cities were predominantly located in the southern and northern coastal areas. An economic foundation and innovation potential have a positive and stable impact on high-quality coordinated development.